Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting
نویسندگان
چکیده
منابع مشابه
Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting.
Systemic gene delivery systems are needed for therapeutic application to organs that are inaccessible by percutaneous injection. Currently, the main objective is the development of a stable and non-toxic vector that can encapsulate and deliver foreign genetic material to target cells. To this end, DNA, complexed with cationic lipids i.e. DOTAP/DOPE, was encapsulated into lipid nanocapsules (LNC...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2010
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2009.09.044